Neural circuit underlying asthma reinforces the lung’s role as a sensory organ

Nature, Published online: 07 August 2024; doi:10.1038/d41586-024-02564-6

Molecular, anatomical and functional evidence point to a multi-nodal neural circuit that senses allergenic particles in inhaled air and induces exaggerated airway constriction, a hallmark of asthma. This is the first description of a full circuit that starts in the lung and returns to control lung function.