Adipose tissue retains an epigenetic memory of obesity after weight loss
19 November 2024Nature, Published online: 18 November 2024; doi:10.1038/s41586-024-08165-7
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to the problematic ‘yo-yo’ effect often seen with dieting.